Treatment of cancer using hsv mutant

Details Treatment of cancer using hsv mutant Treatment of cancer using hsv mutant

A - Human Necessities

61

K

A61K 35/76 (2006.01) C12N 7/00 (2006.01) C12N 15/38 (2006.01)

Patent

CA 2196315

Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the .gamma.343 gene in the long repeat region (R L) such that the .gamma.34.5 gene is non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.

L'invention se rapporte à l'utilisation d'un mutant du virus de l'herpès comme agent anticancéreux, mutant qui a été modifié dans le gène gamma 34,5 de la région à longue répétition (RL) de sorte que le gène gamma 34,5 ne soit pas fonctionnel, et à la fabrication de médicaments et à des procédés de dépistage du cancer chez des mammifères à l'aide du mutant du HSV.

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