A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/166 (2006.01) A61K 31/198 (2006.01) A61K 31/33 (2006.01) A61K 31/37 (2006.01) A61K 31/4745 (2006.01) A61K 31/496 (2006.01) A61K 31/7034 (2006.01) A61K 38/06 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2708157
In one aspect, the present invention provides a composition and a kit comprising a combination of topoisomerase inhibitor and PARP inhibitor for treatment of cancer. In another aspect, the invention provides a method of treating cancer comprising administering to a subject a combination of topoisomerase inhibitor and PARP inhibitor. In particular, the invention provides compositions and methods for treating cancer in a subject by inhibiting a poly- ADP-ribose polymerase and a topoisomerase, as well as providing formulations and modes of administering such compositions.
Selon un aspect, la présente invention a trait à une composition et à un kit comprenant une combinaison d'inhibiteur de topoïsomérase et d'inhibiteur de PARP pour le traitement du cancer. Selon un autre aspect, l'invention a trait à un procédé permettant de traiter le cancer qui comprend l'étape consistant à administrer à un sujet une combinaison d'inhibiteur de topoïsomérase et d'inhibiteur dePARP. En particulier, l'invention a trait à des compositions et à des procédés permettant de traiter le cancer chez un sujet en inhibant une poly(ADP-ribose) polymérase et une topoïsomérase, tout en fournissant des formulations et des modes d'administration de ces compositions.
Bradley Charles
Ossovskaya Valeria S.
Sherman Barry M.
Bipar Sciences Inc.
Goudreau Gage Dubuc
LandOfFree
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