Treatment of cancers with acquired resistance to kit inhibitors

Details Treatment of cancers with acquired resistance to kit inhibitors Treatment of cancers with acquired resistance to kit inhibitors

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2675980

The present invention provides compositions and uses thereof for treating cancers which have acquired resistance to a KIT inhibitor by administering effective amounts of DAST ( 4{4-[3-(4-chloro-3- trifluoromethylphenyf)-ureido]-3-fluorophenoxy}-pyridine -2-carboxylic acid methylamide.)

La présente invention concerne des compositions et procédés permettant de traiter des cancers qui ont acquis une résistance à un inhibiteur KIT, par administration de quantités suffisantes de DAST.

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