Treatment of cardiac hypertrophy using interferon-gamma

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/21 (2006.01) A61K 31/135 (2006.01) A61K 31/275 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2325442

The invention concerns the treatment of cardiac hypertrophy by interferon- gamma (IFN-.gamma.). Cardiac hypertrophy may result from a variety of diverse pathologic conditions, including myocardial infarction, hypertension, hypertrophic cardiomyopathy, and valvular regurgitation. The treatment extends to all stages of the progression of cardiac hypertrophy, with or without structural damage of the heart muscle, regardless of the underlying cardiac disorder.

Cette invention se rapporte au traitement de l'hypertrophie cardiaque par l'interféron-gamma (IFN-.gamma.). L'hypertrophie cardiaque peut provenir d'une grande variété d'états pathologiques divers, tels que l'infarctus du myocarde, l'hypertension, la cardiomyopathie hypertrophique et la régurgitation valvulaire. Ce traitement s'étend à tous les stades de l'évolution de l'hypertrophie cardiaque, avec ou sans dommages structuraux du muscle cardiaque, quel que soit le trouble cardiaque sous-jacent.

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