Treatment of cardiovascular and related pathologies

A - Human Necessities – 61 – K

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Details

A61K 31/675 (2006.01) A61K 31/44 (2006.01) A61K 31/4415 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2368775

Compositions and methods for treatment and prevention of hypertrophy, hypertension, congestive heart failure, is--chemic heart disease, ischemia-related conditions, such as ischemia reperfusion injury and cellular dysfunction, are described. The methods are directed to administering pharmaceutical compositions containing at least one compound selected from pyridoxal-5'--phosphate, pyridoxine, pyridoxal, and pyridoxamine.

L'invention concerne des compositions et des méthodes pour le traitement et la prévention de l'hypertrophie, l'hypertension, l'insuffisance cardiaque globale, la cardiopathie ischémique, d'états liés à l'ischémie, tels que les lésions consécutives à la perfusion au cours d'une ischémie et le dysfonctionnement cellulaire. Les méthodes de l'invention consistent à administrer des compositions pharmaceutiques contenant au moins un composé choisi par pyridoxal-5'-phosphate, pyridoxine, pyridoxal et pyridoxamine.

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