C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/048 (2006.01) A61K 31/00 (2006.01) A61K 31/138 (2006.01) A61K 31/165 (2006.01) A61K 31/277 (2006.01) A61K 31/341 (2006.01) A61K 31/401 (2006.01) A61K 31/417 (2006.01) A61K 31/4355 (2006.01) A61K 31/4415 (2006.01) A61K 31/4422 (2006.01) A61K 31/4965 (2006.01) A61K 31/506 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61K 31/554 (2006.01) A61K 31/616 (2006.01) A61K 31/675 (2006.01) A61K 31/727 (2006.01) A61K 38/55 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P
Patent
CA 2383252
Methods for treating cardiovascular and related diseases such as hypertrophy, hypertension, congestive heart failure, ischemia, ischemia reperfusion injuries in various organs, arrhythmia, and myocardial infarction, are described. The methods are directed to concurrently administering a compound such as pyridoxal-5'-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with a therapeutic cardiovascular compound.
L'invention concerne des procédés relatifs au traitement des maladies cardio-vasculaires et connexes, à savoir par exemple: hypertrophie, hypertension, insuffisance cardiaque globale, ischémie, lésions dans plusieurs organes dues à la reperfusion au cours d'une ischémie, arythmie, et infarctus du myocarde. L'invention concerne également des procédés visant à administrer simultanément un composé du type pyridoxal-5'-phosphate, pyridoxamine, pyridoxal, ou un analogue de pyridoxal 3-acylé, et un composé thérapeutique cardio-vasculaire.
Haque Wasimul
Sethi Rajat
Medicure International Inc.
Ridout & Maybee Llp
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