Treatment of central nervous system disorders with imidazole...

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01) A61K 31/41 (2006.01) A61K 31/4174 (2006.01) A61K 31/495 (2006.01) A61K 31/54 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2078106

Substituted imidazoles such as 2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5- yl)biphenyl-4-yl)methyl]-5-(hydroxymethyl)imidazole and 2-butyl-4-chloro-1-[(2'-carboxybiphenyl-4-yl)-methyl]-5- (hydroxymethyl)imidazole and pharmaceutically acceptable salts thereof are useful for treating central nervous system disorders, such as cognitive and learning disorders, mediated by angiotensin II.

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