A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/04 (2006.01) A61K 35/74 (2006.01)
Patent
CA 2065286
The invention relates to the use of antigenic and/or immunoregulatory material derived from Mycobacterium vaccae for use in the manufacture of a therapeutic agent for the treatment of pathological condition (other than tuberculosis, leprosy or rheumatoid arthritis) in a patient in which the patient's IgG shows an abnormally high proportion of agalactosyl IgG or in the treatment of a chronic inflammatory disorder (other than rheumatoid arthritis) caused or accompanied by an abnormally high release by macrophages of interleukin-6 and/or tumour necrosis factor.
L'invention concerne l'emploi d'une matière antigénique et/ou immunorégulatrice dérivée de Mycobacterium vaccae, destinée à être utilisée dans la fabrication d'un agent thérapeutique permettant le traitement d'états pathologiques (différents de la tuberculose, de la lèpre ou de la polyarthrite chronique rhumatismale) chez un patient, dans lesquels l'IgG (immunoglobuline de type G) du patient présente une proportion anormalement élevée d'IgG d'agalactosyle, ou dans le traitement d'un trouble inflammatoire chronique (différent de la polyarthrite chronique rhumatismale) provoqué ou accompagné par la libération anormalement élevée par les macrophages d'interleukine-6 et/ou de facteur de nécrose tumorale.
Rook Graham A. W.
Stanford John L.
Mccarthy Tetrault Llp
Stanford Rook Limited
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