Treatment of chronic renal failure and other conditions in...

A - Human Necessities – 61 – F

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Details

A61F 2/06 (2006.01) A61K 31/22 (2006.01) A61K 31/366 (2006.01) A61K 31/401 (2006.01)

Patent

CA 2619643

The present invention generally concerns the management of age-related diseases in domestic animals. Specifically, the present invention is directed to combination therapies for the treatment of progressive renal diseases (e.g., Chronic Renal Failure) and their accompanying secondary disease states. In a composition aspect, the present invention provides a composition comprising a phosphate binder and another pharmaceutically active ingredient. The other pharmaceutically active ingredient is selected from a group consisting of antihypertensives, calcitrol, vitamin D analogues, lipid restriction products, potassium salts, treatments for anemia and alkalization compounds.

L'invention concerne en général la gestion des maladies associées au vieillissement chez les animaux domestiques. De manière spécifique, l'invention concerne des polythérapies pour le traitement de maladies rénales progressives (par exemple, l'insuffisance rénale chronique) et les états pathologiques secondaires associés. Selon un aspect, l'invention propose une composition qui comprend un chélateur de phosphate et un autre ingrédient actif sur le plan pharmaceutique. L'autre ingrédient actif sur le plan pharmaceutique est sélectionné dans le groupe comprenant : antihypertenseurs, calcitrol, analogues de la vitamine D, produits de restriction lipidique, sels de potassium, composés d'alcalinisation et de traitement de l'anémie.

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