Treatment of cns disorders using cns target modulators

Details Treatment of cns disorders using cns target modulators Treatment of cns disorders using cns target modulators

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/445 (2006.01) A61K 31/4523 (2006.01) A61K 31/454 (2006.01) A61K 47/48 (2006.01) C07D 211/14 (2006.01) C07D 211/44 (2006.01) C07D 211/46 (2006.01) C07D 211/70 (2006.01) C07D 213/38 (2006.01) C07D 213/55 (2006.01) C07D 313/12 (2006.01) C07D 401/06 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2463579

The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using compositions that remain active for a discrete period of time to reduce side effects. More specifically, the invention is directed to the compositions and use of derivatized, e.g., ester or carboxylic acid derivatized, antihistamine antagonists for the treatment of sleep disorders.

Cette invention, qui a trait à des compositions utilisées pour traiter des troubles du système nerveux central, concerne également des méthodes thérapeutiques à l'encontre de troubles de ce système. Elle porte, en outre, sur des méthodes de traitement de troubles du sommeil, utilisant des compositions restant actives pendant une période temporelle discrète et ce, afin de réduire les effets secondaires. Elle porte, plus précisément, sur les compositions susmentionnées ainsi que sur l'utilisation, notamment, d'ester ou d'acide carboxylique dérivés et d'antagonistes de l'antihistamine pour traiter des troubles du sommeil.

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