Treatment of cognitive impairment using a selective dopamine...

A - Human Necessities – 61 – K

Patent

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A61K 31/44 (2006.01) A61K 31/38 (2006.01)

Patent

CA 2501781

Methods of using DAS-431 under conditions where it is administered at a dose that results in improved cognitive performance but without significant side effects are provided. Symptoms can be ameliorated during the period of treatment and, frequently, for substantially longer periods thereafter. In addition, the DAS-431 is provided at a level which does not negatively affect responsiveness to subsequent doses of DAS-431. Few adverse effects are observed, and the treatments can result in long term relief, so as to avoid frequent repetitive treatment.

L'invention concerne des procédés utilisant du DAS-431 dans des conditions d'administration d'une dose offrant une performance intellectuelle améliorée, mais sans effets secondaires trop importants. Les symptômes peuvent être améliorés durant la période de traitement et, fréquemment, pour une période sensiblement longue après le traitement. En outre, le DAS-431 est fourni à un niveau n'affectant pas négativement la réaction à des doses ultérieures de DAS-431. De rares effets secondaires sont observés et les traitements permettent de soulager à long terme, ce qui évite un traitement répétitif fréquent.

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