A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61P 1/16 (2006.01) A61P 9/00 (2006.01) A61P 21/00 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2595942
Methods and compositions comprising vectors expressing XIAP or XIAP protein preparations for the treatment of degenerative disorders including retinal degeneration, skeletal muscular atrophy, spmal muscular atrophy (SMA), spmobulbar muscular atrophy (SBMA), amyolateral sclerosis (ALS), muscular dystrophy, Parkinson's disease, cardiac injury, and liver disease, and for the reduction of cell apoptosis during transplantation of cells are provided.
Cette invention concerne des méthodes et des compositions comprenant des vecteurs exprimant XIAP ou des préparations protéiques de XIAP et servant au traitement de troubles dégénératifs tels que la dégénérescence rétinienne, l'amyotrophie du squelette, l'amyotrophie spinale (SMA), l'amyotrophie spinobulbaire (SBMA), la sclérose amyolatérale (ALS), la dystrophie musculaire, la maladie de Parkinson, la lésion cardiaque et la maladie hépatique, et à la réduction de l'apoptose cellulaire lors de la transplantation de cellules.
Gendron Nathalie
Korneluk Robert G.
Liston Peter
Mackenzie Alex E.
Mahoney Doug
Children's Hospital Of Eastern Ontario
Gowling Lafleur Henderson Llp
LandOfFree
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