C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) C12N 15/113 (2010.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2755404
The present invention relates to antisense oligonucleotides that modulate the expression of and / or function of Delta- like (1) homolog (DLK1), in particular, by targeting natural antisense polynucleotides of Delta-like (1) homolog (DLK1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of (DLK1).
Cette invention concerne des oligonucléotides antisens qui modulent l'expression et/ou la fonction de l'homologue du Delta-like (1) (DLK1), en particulier, par ciblage des polynucléotides antisens naturels de l'homologue du Delta-like (1) (DLK1). L'invention concerne également l'identification de ces oligonucléotides antisens et leur utilisation pour traiter les maladies et les troubles associés à l'expression de (DLK1).
Coito Carlos
Collard Joseph
Khorkova Sherman Olga
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Opko Curna Llc
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