Treatment of diabetes with thiazolidinedione and sulphonylurea

A - Human Necessities – 61 – K

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A61K 31/64 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2297115

A method for the treatment of diabetes mellitus and conditions associated with diabetes mellitus in a mammal, which method comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitiser and a sub-maximal amount of an insulin secretagogue, to a mammal in need thereof; and a pharmaceutical composition for use in such method.

L'invention concerne une méthode de traitement du diabète sucré et d'états associés au diabète sucré chez un mammifère. Cette méthode consiste à administrer une dose pharmaceutiquement acceptable, non toxique et efficace d'un sensibilisateur à l'insuline, ainsi qu'une dose presque maximale d'un sécrétagogue d'insuline à un mammifère qui en a besoin. L'invention concerne également une composition pharmaceutique destinée à l'utilisation dans cette méthode.

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