Treatment of disease using an improved regulated expression...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/63 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2608764

The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.

La présente invention concerne un système d'expression amélioré pour l'expression régulée d'une protéine codée ou d'une molécule d'acide nucléique dans les cellules d'un sujet, destiné à être utilisé dans le traitement de maladies. La présente invention concerne notamment un système d'expression génétique régulée, amélioré, ainsi que des compositions pharmaceutiques et leurs utilisations pour le traitement de maladies.

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