A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2615636
A method of reducing or preventing hypertension associated with administration of a vascular endothelial growth factor (VEGF) antagonist in a human subjects suffering from a disease or condition treatable with a VEGF antagonist in which is it desirable to reduce or prevent hypertension, wherein a VEGF antagonist is to be administered subcutaneously. The method is particularly useful for treatment of patients unresponsive to treatment with a VEGF inhibitor administered intravenously.
La présente invention concerne un procédé permettant de réduire ou prévenir l'hypertension associée à l'administration d'un antagoniste du facteur de croissance de l'endothélium vasculaire (FCEV) chez des humains atteints d'un état ou d'une affection justifiant d'un traitement par un antagoniste du FCEV pour lequel il convient de réduire ou prévenir l'hypertension. Ce procédé convient particulièrement pour le traitement de patients ne réagissant pas au traitement d'un inhibiteur du FCEV s'administrant par voie veineuse.
Cedarbaum Jesse M.
Furfine Eric
Stahl Neil
Yancopoulos George D.
Blake Cassels & Graydon Llp
Regeneron Pharmaceuticals Inc.
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