A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/197 (2006.01) A61K 31/10 (2006.01) A61K 31/18 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2593523
.alpha.,.beta.-Unsaturated sulfones, sulfoxides and sulfonamides according to Formula I: wherein Ar1, Ar2, X, n, * and R are as defined herein are useful for the treatment of proliferative disorders which are resistant to treatment by ATP-competitive kinase inhibitors.
L'invention concerne des sulfones .alpha.,.beta.-insaturées, des sulfoxydes et des sulfamides représentés par la formule générale (I). Dans cette formule, Ar1, Ar2, X, n * et R désignent des éléments décrits dans la description de la présente demande. Ces composés sont destinés au traitement de maladies proliférantes résistantes aux inhibiteurs de kinases compétitifs de l'ATP.
Baker Stacey J.
Cosenza Stephen C.
Reddy E. Premkumar
Reddy M.v. Ramana
Mccarthy Tetrault Llp
Temple University - Of The Commonwealth System Of Higher Educati
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