Treatment of duchenne muscular dystrophy

Details Treatment of duchenne muscular dystrophy Treatment of duchenne muscular dystrophy

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 21/00 (2006.01) C07D 249/20 (2006.01)

Patent

CA 2685582

There are provided compounds of Formula (I) wherein three of A1, A2, A3, and A4 represent CH and one of A1, A2, A3, and A4 represents CR1; R1 represents SO2R2 or NHCOR2 wherein R2 represents C1-C6 alkyl optionally substituted by one or more halogen, hydroxyl or alkoxy groups; R9 represents C6-C10 aryl; or a pharmaceutically acceptable salt thereof and method of treatment of Duchenne muscular dystrophy.

L'invention concerne des composés de la formule (I) dans laquelle trois éléments parmi A1, A2, A3, et A4 représentent CH et un élément parmi A1, A2, A3, et A4 représente CR1; R1 représente SO2R2 ou NHCOR2 où R2 représente un C1-C6 alkyle facultativement substitué par un ou plusieurs groupes halogène, hydroxyle ou alcoxy; R9 représente un C6-C10 aryle; ou un sel pharmaceutiquement acceptable de ces derniers.

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