Treatment of dyskinesia

Details Treatment of dyskinesia Treatment of dyskinesia

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61K 31/4184 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2338066

The invention relates to the use of compounds which inhibit selectively mu opioid receptor activity, or activation, for the treatment of dyskinesia (which, for example, may arise as a side effect of L-DOPA therapy). The compounds used are preferably mu opioid receptor; antagonists such as cyprodime.

L'invention concerne l'utilisation de composés inhibant de façon sélective l'activité, ou l'activation, du récepteur de mu-opioïdes, afin de traiter la dyskinésie (pouvant, par exemple, apparaître en tant qu'effet secondaire d'une thérapie à L-DOPA). Ces composés, sont, de préférence, des antagonistes du récepteur de mu-opioïdes, tels que cyprodime).

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