C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/113 (2010.01) C12N 5/071 (2010.01) A61K 31/7088 (2006.01) A61K 31/712 (2006.01) A61K 31/7125 (2006.01) A61K 31/713 (2006.01) C12N 15/00 (2006.01) C12N 15/12 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) C07K 14/505 (2006.01)
Patent
CA 2745329
Oligonucleotide compounds modulate expression and/or function of Erythropoietin (EPO) polynucleotides and encoded products thereof. Methods for treating diseases associated with Erythropoietin (EPO) comprise administering one or more oligonucleotide compounds designed to inhibit the EPO natural antisense transcript to patients.
La présente invention porte sur des composés oligonucléotidiques qui modulent l'expression et/ou la fonction de polynucléotides d'érythropoïétine (EPO) et sur des produits codés par ceux-ci. L'invention porte également sur des méthodes de traitement de maladies associées à l'érythropoïétine (EPO) comprenant l'administration d'un ou de plusieurs composés oligonucléotidiques conçus pour inhiber le transcrit antisens naturel de l'EPO chez des patients.
Collard Joseph
Khorkova Sherman Olga
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Opko Curna Llc
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