Treatment of eye disorders with sirtuin modulators

A - Human Necessities – 61 – K

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A61K 31/05 (2006.01) A61K 31/353 (2006.01) A61K 31/56 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2603009

Sirtuin modulators, particularly sirtuin activators, are useful in treating vision impairment. In general, the sirtuin modulators inhibit the progression of vision impairment resulting from various eye disorders. The invention also includes pharmaceutically acceptable formulations of sirtuin modulators, particular ophthalmically acceptable formulations.

Des modulateurs de sirtuine, en particulier des activateurs de sirtuine, sont utiles dans le traitement d'une déficience de la vision. D'une manière générale, les modulateurs de sirtuine empêchent la progression d'une déficience de la vision résultant de divers troubles oculaires. L'invention comprend également des formulations pharmaceutiquement acceptables de modulateurs de sirtuine et en particulier des formulations acceptables sur le plan ophtalmique.

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