A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/56 (2006.01)
Patent
CA 2559476
The present invention relates to a method for inhibiting fibrosis that occurs in an organ where the farnesoid X receptor (FXR) is expressed. This method involves the step of administering a high potency, activating ligand of FXR in an effective amount to a patient who is not suffering from a cholestatic condition. The invention also provides pharmaceutical compositions containing an effective amount of an FXR ligand and kits for dispensing the pharmaceutical compositions.
L'invention concerne un procédé qui permet d'inhiber la fibrose qui se déclare dans un organe où le récepteur FXR (farnesoid X receptor) est exprimé. Cette méthode consiste à administrer un ligand activateur à haute dose de FXR à une quantité efficace à un patient qui ne souffre pas d'une maladie cholestatique. L'invention concerne également des compositions pharmaceutiques contenant une quantité efficace d'un ligand FXR et des trousses permettant de distribuer ces compositions pharmaceutiques.
Fiorucci Stefano
Pellicciari Roberto
Pruzanski Mark
Fetherstonhaugh & Co.
Intercept Pharmaceuticals Inc.
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