Treatment of gallstones

Details Treatment of gallstones Treatment of gallstones

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2368416

A compound of formula (I) or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example N,N-dimethyl-1-[1- (4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating gallstones, particulary gallstones associated with weight loss or associated with gall bladder disease related to obesity.

La présente invention concerne un composé représenté par la formule générale (I), ou l'un de ses sels pharmaceutiquement admis, convenant particulièrement pour le traitement des calculs biliaires, et plus particulièrement les calculs biliaires associés à une perte de poids ou associés à une atteinte de la vésicule biliaire en relation avec l'obésité. Dans cette formule, R¿1? et R¿2? sont indépendamment H ou méthyle, notamment l'hydrochlorure de N,N-diméthyl-1-[1-(4-chlorophényl)cyclobutyl]-3-méthylbutylamine, éventuellement sous sa forme monohydrate.

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