A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/205
A61K 31/557 (2006.01)
Patent
CA 1209044
TREATMENT OF GASTRIC INFLAMMATORY DISEASE WITH CYTOPROTECTIVE PROSTAGLANDINS AND HISTAMINE-2 RECEPTOR BLOCKING ANTI-SECRETORY AGENTS ABSTRACT Compositions comprising gastric cytoprotective prostaglandin or prostaglandin-like compounds and histamine-2 receptor blocking anti-secretory agents useful in the treatment and prophylaxis of gastric inflammatory conditions are disclosed. These compositions are effective in the treatment and prophylaxis of gastro-intestinal ulceration. They utilize levels of both prostaglandin and anti-sec- retory agents which are significantly lower than ordinarily required as the prostaglandin potentiates the effect of the anti-secretory agent, and minimizes the side effects which are frequently associ- ated with the administration of prostaglandins. The method of treating and preventing gastric inflammatory diseases using these compositions is also disclosed.
440524
Matthews Randall S.
Wagner Gregory S.
Gowling Lafleur Henderson Llp
The Procter & Gamble Company
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