Treatment of hepatitis b virus infection with human...

A - Human Necessities – 61 – K

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Details

A61K 31/42 (2006.01) A61K 31/20 (2006.01) A61K 31/70 (2006.01) A61K 39/42 (2006.01) C07K 16/08 (2006.01)

Patent

CA 2462427

Disclosed is a pharmaceutical composition for the treatment or prevention of hepatitis B virus infection, comprising a 1:3 mixture of two fully human anti HBsAg monoclonal antibodies 19.79 and 17.1.41. Alto disclosed are preferred modes of administration. The pharmaceutical composition can be given as a monotherapy or in combination with other anti viral agents.

Cette invention se rapporte à une composition pharmaceutique servant au traitement ou à la prévention des infections par le virus de l'hépatite B et comprenant un mélange 1/3 de deux anticorps monoclonaux anti-HBsAg totalement humains 19.79.5 et 17.1.41. Cette invention décrit également des modes préférés d'administration d'une telle composition. Cette composition pharmaceutique peut être administrée en monothérapie ou associée à d'autres agents antiviraux.

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