Treatment of hepatitis c virus infections with interleukin-10

A - Human Necessities – 61 – K

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A61K 38/20 (2006.01) A61K 31/70 (2006.01) A61K 38/21 (2006.01) A61P 1/16 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2356010

The hepatoprotective effect of IL-10 is described, in particular, the use of interleukin-10 in the treatment of liver damage (e.g. fibrosis or cirrhosis) in a difficult-to-treat patient afflicted with chronic hepatitis C virus infection who has failed to respond to, or achieve a sustained virologic response to an anti-HCV therapy (e.g., interferon-.alpha. in combination with ribavirin).

L'invention concerne l'effet hépatoprotecteur d'IL-10, en particulier, l'utilisation de l'interleukine-10 dans le traitement d'atteintes hépatiques (p. ex. la fibrose ou la cirrhose) chez un patient difficile à traiter souffrant du virus de l'hépatite C chronique qui n'a pas donné une réponse virologique soutenue ou n'a pas répondu au traitement anti-VHC (notamment l'interféron-.alpha. combiné à la ribavirine).

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