Treatment of hiatial hernia

Details Treatment of hiatial hernia Treatment of hiatial hernia

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2367035

A compound of formula (I), or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl (for example <u>N</u>, <u>N</u>- dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl amine hydrochloride optionally in the form of its monohydrate) is used for treating hiatial hernias and reflux esophagitis.

L'invention concerne un composé correspondant à la formule (I) ou un sel de celui-ci, acceptable sur le plan pharmacologique. Dans cette formule, R¿1? et R¿2? représentent indépendamment H ou méthyle (par exemple du chlorhydrate de <u>N</u>, <u>N</u>-diméthyl-1-[1-(4-chlorophényl)cyclobutyl]-3-méthylbutylamine éventuellement sous la forme de son monohydrate). Ce composé est utile dans le traitement des hernies hiatales et dans l'oesophagite par reflux.

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