A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/167 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01)
Patent
CA 2682266
Compositions comprising CD80 antagonists and methods using these compositions are provided for the treatment of Hodgkins lymphoma. More particularly, the disclosed CD80 antagonists may be used to induce apoptosis or lysis of Hodgkins Reed-Sternberg (HRS) cells, or to inhibit HRS cell activities that promote tumor development or progression.
L'invention propose des compositions comportant des antagonistes CD80 et des procédés d'utilisation de ces compositions pour le traitement de la maladie de Hodgkin. Plus particulièrement, les antagonistes CD80 décrits peuvent être utilisés pour induire une apoptose ou une lyse de cellules de Hodgkin Reed-Sternberg (HRS) ou pour inhiber des activités de cellules HRS qui favorisent le développement ou la progression de tumeur.
Hariharan Kandasamy
Ho Steffan
Molina Arturo
Biogen Idec Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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