Treatment of hyperproliferative diseases with vinca alkaloid...

C - Chemistry – Metallurgy – 07 – D

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C07D 519/04 (2006.01) A61K 31/475 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2642717

The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.

L'invention concerne des N-oxydes d'alcaloïde de la pervenche et d'analogues possédant une activité destinée à traiter des troubles hyperprolifératifs. L'invention concerne également des compositions pharmaceutiques et des procédés utilisant ces N-oxydes d'alcaloïde de la pervenche et d'analogues, seul ou en combinaison avec un ou plusieurs autres agents ou traitements actifs, en vue de traiter des troubles hyperprolifératifs.

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