A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/675 (2006.01) A61K 31/4415 (2006.01) A61P 9/12 (2006.01) A61K 31/196 (2006.01) A61K 31/405 (2006.01) A61K 31/616 (2006.01)
Patent
CA 2328730
Hypertension in mammalian patients, especially elderly human patients, derived from ingestion of NSAIDs or through the normal aging process is treated by administration to the patient of a vitamin B6 (or derivative) supplement. Where the patient requires the continued administration of an NSAID for pharmacological purposes, the NSAID is administered in conjunction with a vitamin B6 supplement. The invention further provides combination pharmaceutical combinations of an NSAID and a vitamin B6 supplement, e.g. orally administrable tablets or capsules, for use in treating such conditions.
L'invention concerne le traitement de l'hypertension chez des patients mammifères, en particulier chez des patients humains âgés, due à l'ingestion d'anti-inflammatoires non stéroïdiens ou à un processus normal de vieillissement, par l'administration au patient d'un supplément de vitamine B6 (ou d'un dérivé de celle-ci). Lorsque le patient nécessite une administration continue d'un anti-inflammatoire non stéroïdien à des fins pharmacologiques, l'anti-inflammatoire non stéroïdien est administré conjointement avec un supplément de vitamine B6. L'invention concerne en outre des combinaisons pharmaceutiques d'un anti-inflammatoire non stéroïdien et d'un supplément de vitamine B6, p. ex. des comprimés ou des capsules pouvant être administrés par voie orale, utiles pour traiter ces affections.
Dakshinamurti Krishnamurti
Dhalla Naranjan S.
Sethi Rajat
Medicure Inc.
Ridout & Maybee Llp
University Of Manitoba
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