Treatment of infectious disease using interleukin-1 beta...

A - Human Necessities – 61 – K

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Details

A61K 31/55 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2463729

The present invention provides methods and compositions for treating infectious disease or suppressing inflammation associated therewith or ameliorating symptoms thereof by the suppression of the activity of a member of the interleukin-1.szlig.-converting enzyme (ICE)/CED-3 family of proteases. Also provided are compositions useful for these purposes. Exemplary compounds useful in the methods of the invention are provided herein.

L'invention concerne des méthodes et des compositions permettant de traiter une maladie infectieuse, de supprimer une inflammation associée à ladite maladie ou d'améliorer les symptômes de cette maladie par suppression de l'activité d'un membre de la famille CED-3/ICE (enzyme de conversion de l'interleukine-1.szlig.) de protéases. L'invention concerne également des compositions utilisées aux fins précitées. L'invention concerne enfin des composés exemplaires utilisés dans les méthodes précitées.

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