A - Human Necessities – 61 – H
Patent
A - Human Necessities
61
H
A61H 39/04 (2006.01)
Patent
CA 2680477
Described herein are devices, systems and method for treating inflammatory disorders by modulating a subject's inflammatory reflex. The method may include the step of non-invasively stimulating the inflammatory reflex (e.g., the vagus nerve, the splenic nerve, the hepatic nerve, the facial nerve, and the trigeminal nerve) of a subject in a manner which significantly reduces proinflammatory cytokines in the subject and/or provides a therapeutically effective treatment for the subject. Devices for non-invasively stimulating the inflammatory reflex may include a movable tip or actuator that is controlled to mechanically stimulate the ear. The devices may be hand-held or wearable, and may stimulate the cymba conchae region of the subject's ear.
L'invention concerne des dispositifs, des systèmes et un procédé pour traiter des troubles inflammatoires en modulant un réflexe inflammatoire d'un sujet. Le procédé comprend l'étape consistant à stimuler de manière non invasive le réflexe inflammatoire (par exemple le nerf pneumogastrique, le nerf splénique, le nerf hépatique, le nerf facial et le nerf trijumeau) d'un sujet d'une manière qui réduit significativement les cytokines pro-inflammatoires chez les sujets et/ou fournit un traitement thérapeutiquement efficace pour le sujet. Des dispositifs pour stimuler de manière non invasive le réflexe inflammatoire peut comprendre un embout ou actionneur mobile qui est commandé pour stimuler mécaniquement l'oreille. Les dispositifs peuvent être à main ou portables, et peuvent stimuler la région de la cymba conchae de l'oreille du sujet.
Faltys Michael Allen
Huston Jared M.
Tracey Kevin J.
Warren Howland Shaw Jr.
Critical Therapeutics Inc.
Gowling Lafleur Henderson Llp
Setpoint Medical Corporation
The Feinstein Institute For Medical Research
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