Treatment of inflammatory or malignant disease using dnazymes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/00 (2006.01) A61K 38/43 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2380678

The present invention relates to DNAzymes which are targeted against mRNA molecules encoding RelA(p65) (a subunit of NF-.kappa.B).The present invention also relates to compositions including these DNAzymes and to methods of treatment involving administration of the DNAzymes.

La présente invention concerne des DNAzymes qui sont ciblés contre les molécules d'ARN messager codant RelA(p65) (une sous-unité de NF-.kappa.B). Cette invention concerne également des compositions comprenant ces DNAzymes et des procédés de traitement impliquant l'administration de DNAzymes.

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