Treatment of influenza

Details Treatment of influenza Treatment of influenza

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 31/7088 (2006.01) A61K 31/7125 (2006.01) A61K 31/713 (2006.01) A61P 31/18 (2006.01) A61P 43/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2692478

The present invention provides a double-stranded RNA which inhibits replication of influenza B viruses by RNA interference, in which the double-stranded RNA comprises an RNA having 19 to 25 nucleotides homologous with a part of an mRNA transcribed from a genomic RNA of the influenza B viruses and an antisense RNA thereof.

L'invention concerne un ARN double brin qui peut inhiber la réplication d'un virus de la grippe de type B à travers une interférence d'ARN. L'ARN double brin comprend : un ARN qui est constitué de 19 à 25 nucléotides et est homologue avec une partie d'ARNm transcrite par l'ARN génomique d'un virus de la grippe de type B ; et un ARN antisens de l'ARN mentionné ci-dessus.

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