A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 38/16 (2006.01) A61K 51/00 (2006.01) A61P 1/06 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2663377
The present invention relates to the use of receptor-associate protein (RAP) and fragments and variants thereof to improve delivery of therapeutic compounds to the liver and provides methods to treat liver disorders and conditions, such as hepatic carcinoma, by administering RAP or RAP variants conjugated to active agents.
La présente invention concerne l'utilisation de protéine associée au récepteur (Receptor-Associate Protein: RAP) et de fragments ou de variantes de celle-ci pour améliorer la délivrance de composés thérapeutiques dans le foie et elle concerne des procédés de traitement des affections et des troubles hépatiques tels que le carcinome hépatique, par l'administration de RAP ou de variantes de RAP conjuguées à des agents actifs.
Starr Christopher M.
Zankel Todd C.
Raptor Pharmaceutical Inc.
Smart & Biggar
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