Treatment of lung diseases and pre-lung disease conditions

A - Human Necessities – 61 – K

Patent

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A61K 33/24 (2006.01)

Patent

CA 2566174

In part, the present invention relates to a method of treating lung diseases and pre-lung disease conditions such as precancerous lesions comprising administering to a patient in need a therapeutic agent comprising lipid composition. The present invention also relates to an inhalation device for administering lipid complexes comprising therapeutic agents. The inhalation device may be disposable. In one embodiment, the lung diseases pretreated by the methods of the present invention are those diseases associated with tobacco related products. The present invention also relates to a method of preparing liposomes by an infusion method that yields high entrapment percentages.

En partie, la présente invention concerne un procédé de traitement de maladies des poumons et d'affections préalables à des maladies des poumons telles que des lésions précancéreuses comprenant d'administrer à un patient qui en a besoin un agent thérapeutique comprenant une composition de lipides. La présente invention concerne également un dispositif d'inhalation servant à administrer des complexes de lipides comprenant des agents thérapeutiques. Le dispositif d'inhalation peut être jetable. Dans un mode de réalisation, les maladies des poumons prétraitées par les procédés de la présente invention sont les maladies associées aux produits apparentés au tabac. La présente invention concerne également un procédé de préparation de liposomes par un procédé d'infusion qui produit des pourcentages d'encapsulation élevés.

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