Treatment of lupus nephritis with anti-cd40l compounds

Details Treatment of lupus nephritis with anti-cd40l compounds Treatment of lupus nephritis with anti-cd40l compounds

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2277222

Methods are provided for treating nephritis associated with immune complex disease with anti-CD40L compounds. In one embodiment, anti-CD40L compounds are administered to a patient with immune complex disease who has received a kidney allograft, to inhibit the development of immune complex glomerulonephritis within the grafted kidney.

L'invention porte sur des procédés de traitement de la néphropathie associée à une maladie complexe immune au moyen des composés anti-CD40L. Selon une réalisation, on administre les composés anti-CD40L à un patient atteint d'une maladie complexe immune qui a reçu une allogreffe de rein en vue d'inhiber le développement de la glomérulonéphrite complexe immune dans le rein greffé.

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