Treatment of malignant tumors with 8 chloroadenosine...

Details Treatment of malignant tumors with 8 chloroadenosine... Treatment of malignant tumors with 8 chloroadenosine...

C - Chemistry, Metallurgy

07

D

167/202, 260/242

C07D 473/00 (2006.01) A61K 31/70 (2006.01) C07H 19/16 (2006.01) C07H 19/20 (2006.01)

Patent

CA 1326849

TITLE: TREATMENT OF MALIGNANT TUMORS WITH 8-CHLOROADENOSINE 3',5'-cyclic PHOSPHATE, 8-AMINOADENOSINE 3',5'-cyclic PHOSPHATE AND PREPARATION THEREOF ABSTRACT: The compounds 8-chloroadenosine 3',5'-cyclic phosphate and 8-aminoadenosine 3',5'-cyclic phosphate are used together or separately to treat malignant tumors in warm blooded animals. Two novel single step syntheses of 8-chloroadenosine 3',5'- cyclic phosphate and other related adenine and adenosine compounds from corresponding adenosine 3',5'-cyclic phosphate and other respective related adenosine compounds are disclosed.

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