Treatment of medical disorders associated with free radical...

A - Human Necessities – 61 – K

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A61K 31/575 (2006.01) A61K 8/63 (2006.01)

Patent

CA 2170591

A method for the treatment of biochemical damage or a medical disorder associated with free radical formation in a patient comprises administering to the to the patient an effective amount of a bile alcohol or a derivative thereof, particularly 5.beta.-scymnol, 5.beta.-scymnol sulphate, 5.alpha.-cyprinol or 5.alpha.-cyprinol sulphate. The invention includes treatment of photodamage to the skin and/or hair of a patient associated with free radical formation resulting from UV irradiation as well as treatment of inflammatory disorders or conditions of the skin. Compositions, including topical compositions, are also included.

Un procédé de traitement de lésions biochimiques ou d'une affection d'ordre médical asociées à la formation de radicaux libres chez un patient consiste à administrer à ce dernier une dose efficace d'un alcool biliaire ou d'un dérivé de ce dernier, en particulier le 5.beta.-scymnol, du sulfate de 5.beta.-scymnol, du 5.alpha.-cyprinol ou sulfate de 5.alpha.-cyprinol. L'invention se rapporte également au traitement de lésions dermatologiques et/ou capillaires produites par la lumière, et associées à la formation de radicaux libres provoquée par un rayonnement ultraviolet, ainsi qu'au traitement de troubles de ou d'états inflammatoires de la peau. Des compositions sont également décrites, y compris des compositions topiques.

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