Treatment of migraine with n-alkyl-piperidinyl benzoate...

C - Chemistry – Metallurgy – 07 – D

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260/292.6, 260/2

C07D 211/40 (2006.01) C07D 211/42 (2006.01) C07D 211/46 (2006.01)

Patent

CA 1187502

ABSTRACT Migraine is treated with an N-alkyl-(3 or 4)- piperidinyl benzoate compound of general Formula I:- Image (I) wherein: the benzoloxy group is at the 3 or 4 position of the piperidine ring; n is 0, or an integer from 1 to 5; R1 represents C1-C4 alkyl; and each R2 represents C1-C4 alkyl, C1-C4 alkoxy, or halogen, provided that, when n is 2, the groups represented by R2 can be either the same or different, and, when n is 3, 4, or 5, the groups represented by R2 must be the same, or a pharmaceutically acceptable salt thereof.

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