Treatment of mitochondria-related diseases and improvement...

A - Human Necessities – 61 – K

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A61K 31/13 (2006.01) A61K 31/198 (2006.01) A61K 31/325 (2006.01) A61K 31/395 (2006.01) A61K 31/4745 (2006.01) A61K 33/24 (2006.01) A61P 7/00 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2632697

Treatment of mitochondrial related conditions in mammals with antagonists or chelating agents of copper (II), preferably tetramines or penicillamines. These agents affect TGF-beta, Smad 4, collagen IV, cytochrome C oxidase and erectile dysfunction.

L'invention concerne un traitement de conditions liées aux mitochondries chez des mammifères aux moyens d'antagonistes ou d'agents chélateurs du cuivre (II), de préférence des tétramines ou des pénicillamines. Lesdits agents affectent le TGF-bêta, le Smad 4, le collagène IV, la cytochrome C oxydase et la dysfonction érectile.

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