A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2724841
Methods of treating mitochondrial disorders that are not respiratory chain disorders using compositions comprising EPO mimetic compounds or compounds capable of increasing endogenous EPO levels or stimulating erythropoiesis are disclosed. Methods of treating Friedreich's ataxia, Leigh's syndrome, or other disorders by increasing the expression of frataxin with an EPO mimetic compound or a compound capable of increasing endogenous EPO levels or stimulating erythropoiesis are also disclosed.
L'invention porte sur des procédés de traitement de troubles mitochondriaux qui ne sont pas des troubles de la chaîne respiratoire à l'aide de compositions comprenant des composés mimétiques d'EPO ou des composés capables d'augmenter les taux d'EPO endogène ou de stimuler l'érythropoïèse. L'invention porte également sur des procédés de traitement de l'ataxie de Friedreich, du syndrome de Leigh ou autres troubles par l'augmentation de l'expression de la frataxine avec un composé mimétique d'EPO ou un composé capable d'augmenter les taux d'EPO endogène ou de stimuler l'érythropoïèse.
Kheifets Viktoria
Miller Guy M.
Shrader William D.
Borden Ladner Gervais Llp
Edison Pharmaceuticals Inc.
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