Treatment of motor fluctuations

Details Treatment of motor fluctuations Treatment of motor fluctuations

A - Human Necessities

61

K

A61K 31/137 (2006.01) A61K 31/00 (2006.01) A61K 31/136 (2006.01) A61K 31/198 (2006.01) A61K 31/353 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61P 21/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2431641

The invention relates to the use of compounds that enhance 5-hydroxytryptamine 1a receptor activity, or activation (e.g. a selective 5-hydroxytryptamine 1a receptor agonists) for preventing or reducing motor fluctuations associated with dopamine replacement therapy.

L'invention concerne l'utilisation de composés augmentant l'activité du récepteur 1a de la 5-hydroxytryptamine, ou son activation (par exemple, des agonistes sélectifs du récepteur 1a de la 5-hydroxytryptamine) afin d'empêcher ou de réduire des fluctuations motrices associées à une thérapie de remplacement de la dopamine.

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