Treatment of movement disorders

Details Treatment of movement disorders Treatment of movement disorders

A - Human Necessities

61

K

A61K 31/196 (2006.01) A61K 31/00 (2006.01) A61K 31/192 (2006.01) A61K 31/198 (2006.01) A61K 31/353 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/55 (2006.01) A61K 31/655 (2006.01) A61K 45/06 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2404049

The present invention relates to the use of compounds, which inhibit metabotropic glutamate receptor activity, or activation, for use in the treatment of movement disorders associated with a poverty of movement (e.g. Parkinson's disease). The compounds are particularly useful when used in combination with another therapeutic agent and surprisingly reduce the extent and incidence of side effects (e.g. dyskinesia) associated with such therapeutic agents.

L'invention concerne l'utilisation de composés qui inhibent l'activité ou l'activation des récepteurs du glutamate métabotropique pour traiter des troubles des mouvements associés à une rareté des mouvements (p. ex. maladie de Parkinson). Les composés sont particulièrement utiles en combinaison avec un autre agent thérapeutique et réduisent de manière surprenante l'étendue et l'apparition d'effets secondaires (p. ex. dyskinésie) associés à ces agents thérapeutiques.

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