A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/225 (2006.01) A61K 31/00 (2006.01) A61K 31/195 (2006.01) A61K 31/22 (2006.01)
Patent
CA 2494503
A method of treating multiple sclerosis, the method comprises administering to a subject in need thereof a therapeutically effective amount of a compound, the compound having: (a) a combination of molecular weight and membrane miscibility properties for permitting the compound to cross the blood brain barrier of the organism; (b) a readily oxidizable chemical group for exerting antioxidation properties; and (c) a chemical make-up for permitting the compound or its intracellular derivative to accumulate within the cytoplasm of cells.
L'invention concerne un procédé de traitement de la sclérose en plaques, consistant à administrer à un sujet en demande, une quantité thérapeutiquement efficace d'un composé, ledit composé présentant (a) une combinaison de poids moléculaires et de propriétés de miscibilité membranaire, permettant audit composé de franchir la barrière hémato-encéphalique de l'organisme ; (b) un groupe chimique facilement oxydable exerçant des propriétés d'antioxydation ; et (c) un agencement chimique permettant audit composé ou à son dérivé intracellulaire de s'accumuler dans le cytoplasme des cellules.
Atlas Daphne
Melamed Eldad
Offen Daniel
Mor - Research Applications Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ramot At Tel-Aviv University Ltd.
Yissum Research Development Company Of The Hebrew University Of
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