Treatment of myeoproliferative diseases

A - Human Necessities – 61 – K

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A61K 31/635 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2662320

Methods of reducing the number of platelets in mammals and preventing or treating pro-thrombotic conditions and diseases that are characterized by an excess of, or undesired activation of, platelets using inhibitors of anti apoptotic Bcl-2 family protein members is disclosed.

La présente invention concerne des procédés permettant de réduire le nombre de plaquettes sanguines chez les mammifères et de prévenir ou de traiter les affections et les maladies prothrombotiques qui se caractérisent par un excès de plaquettes ou une activation non désirée des plaquettes à l'aide d'inhibiteurs des membres de la famille des protéines antiapoptotiques Bcl-2.

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