C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61K 31/5377 (2006.01) A61P 25/02 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2492022
6H-pyrrolo[3,4-d]pyridazine compounds and methods of their use of as ligands of voltage gated calcium channels (VGCC), useful in the treatment of neuropathic pain, and psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, panic, and bipolar disorder, as well as in the treatment of pain, Parkinson s disease, cognitive dysfunction, epilepsy, circadian rhythm disorders, drug addiction, drug abuse, drug withdrawal and other
L'invention concerne des composés 6<I>H</I>-pyrrolo[3,4-d]pyridazine ainsi que leurs méthodes d'utilisation en tant que ligands de canaux calciques dépendant d'un potentiel d'action (VGCC), utiles dans le traitement de la douleur neuropathique, et de troubles psychiatriques et de l'humeur tels que, la schizophrénie, l'anxiété, la dépression, la panique et le trouble bipolaire, ainsi que dans le traitement de la douleur, de la maladie de Parkinson, du dysfonctionnement cognitif, de l'épilepsie, rythme nycthéméral, de la toxicomanie, de l'abus des drogues, du sevrage de drogue, etc.
Anker Naomi Burke
Arruda Jeannie M.
Campbell Brian Thomas
Hu Tao
Munoz Benito
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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