Treatment of ocular diseases

A - Human Necessities – 61 – K

Patent

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A61K 38/48 (2006.01)

Patent

CA 2658564

The present invention relates to the use of at least one protease for the manufacture of a medicament for the treatment and/or prevention of ocular diseases related to neoangiogenesis selected from the group consisting of age related macular degeneration (AMD), choroidal neovascularisation, Hippel-Lindau Disease, iris neovascularisation, ischemic proliferative retinopathy, neovascularisation of the Cornea, and proliferative sickle cell retinopathy, wherein the at least one protease is selected from the group consisting of plant, non-mammalian animal and microbial proteases.

La présente invention concerne l'utilisation d'au moins une protéase pour la fabrication d'un médicament destiné au traitement et/ou à la prévention de maladies oculaires associées à une néoangiogenèse et choisies parmi une dégénérescence maculaire liée à l'âge (DMLA), une néovascularisation choroïdienne, la maladie de Von Hippel-Lindau, une néovascularisation de l'iris, une rétinopathie ischémique proliférante, une néovascularisation de la cornée, et une rétinopathie drépanocytaire proliférante, ladite ou lesdites protéases étant choisies parmi des protéases de végétaux, d'animaux non mammaliens et de microbes.

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