Treatment of papillomavirus-associated lesions using...

Details Treatment of papillomavirus-associated lesions using... Treatment of papillomavirus-associated lesions using...

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 31/70 (2006.01) A61K 39/12 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2215525

Interleukin-12 (IL-12) or a functional analogue thereof, or a polynucleotide encoding IL-12 or encoding a functional analogue thereof, is used as a therapeutic material or adjuvant in treating papillomavirus-associated lesions e.g. warts due to HPV 6 and/or 11, e.g. condylomaacuminata. IL-12 or a vector encoding it for endogenous production can be used together with a vaccine such as a papillomavirus antigen, or a vector encoding a papillomavirus antigen.

On utilise l'interleukine-12 (IL-12) ou un de ses analogues fonctionnels, ou encore un polynucléotide codant l'interleukine-12 ou codant un de ses analogues fonctionnels, comme substance thérapeutique ou comme adjuvant dans le traitement de lésions liées au virus du papillome, notamment de verrues causées par le virus du papillome humain (VPH) 6 et/ou 11, notamment le condylome acuminé. Pour développer une production l'IL-12 ou un vecteur en codant la production endogène peut s'utiliser en association avec un vaccin tel qu'un antigène du papillome, ou un vecteur codant un antigène du papillome.

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