A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/66 (2006.01)
Patent
CA 2122498
2122498 9311774 PCTABS00022 This invention claims a method for treating periodontal disease in mammals, including humans, by administering an effective amount of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or a pharmaceutically acceptable salt including the monosodium salt tridydrate (alendronate) of formula (I). The compounds are useful in the treatment of alveolar bone loss associated with periodontitis and periodontal disease.
Gertz Barry J.
Rodan Gideon A.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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